Publications

2017 (8)

Omar MH, Campbell MK, Xiao X, Zhong Q, Brunken WJ, Miner JH, Greer CA, Koleske AJ: CNS Neurons Deposit Laminin α5 to Stabilize Synapses. Cell Rep. 2017 Oct 31. PMID: 29091766

Shapiro LP, Omar MH, Koleske AJ, Gourley SL: Corticosteroid-induced dendrite loss and behavioral deficiencies can be blocked by activation of Abl2/Arg kinase. Mol Cell Neurosci. 2017 Oct 26; 2017 Oct 26. PMID: 29107098

Katrancha SM, Wu Y, Zhu M, Eipper BA, Koleske AJ, Mains RE: Neurodevelopmental disease-associated de novo mutations and rare sequence variants affect TRIO GDP/GTP exchange factor activity. Hum Mol Genet. 2017 Sep 14; 2017 Sep 14. PMID: 28973398

Ganesan S, Luu TT, Chambers BJ, Meinke S, Brodin P, Vivier E, Wetzel DM, Koleske AJ, Kadri N, Höglund P: The Abl-1 Kinase is Dispensable for NK Cell Inhibitory Signalling and is not Involved in Murine NK Cell Education. Scand J Immunol. 2017 Sep. PMID: 28605050

Thompson AD, Omar MH, Rivera-Molina F, Xi Z, Koleske AJ, Toomre DK, Schepartz A: Long-Term Live-Cell STED Nanoscopy of Primary and Cultured Cells with the Plasma Membrane HIDE Probe DiI-SiR.Angew Chem Int Ed Engl. 2017 Aug 21; 2017 Jul 24. PMID: 28679029

Miller MB, Yan Y, Machida K, Kiraly DD, Levy AD, Wu YI, Lam TT, Abbott T, Koleske AJ, Eipper BA, Mains RE: Brain Region and Isoform-Specific Phosphorylation Alters Kalirin SH2 Domain Interaction Sites and Calpain Sensitivity. ACS Chem Neurosci. 2017 Jul 19; 2017 Apr 25. PMID: 28418645

Rosenberg BJ, Gil-Henn H, Mader CC, Halo T, Yin T, Condeelis J, Machida K, Wu YI, Koleske AJ: Phosphorylated cortactin recruits Vav2 guanine nucleotide exchange factor to activate Rac3 and promote invadopodial function in invasive breast cancer cells. Mol Biol Cell. 2017 May 15; 2017 Mar 29. PMID: 28356423

Shapiro LP, Parsons RG, Koleske AJ, Gourley SL: Differential expression of cytoskeletal regulatory factors in the adolescent prefrontal cortex: Implications for cortical development. J Neurosci Res. 2017 May; 2016 Oct 13. PMID: 27735056


2016 (3)

Matsumoto Y, La Rose J, Kent OA, Wagner MJ, Narimatsu M, Levy AD, Omar MH, Tong J, Krieger JR, Riggs E, Storozhuk Y, Pasquale J, Ventura M, Yeganeh B, Post M, Moran MF, Grynpas MD, Wrana JL, Superti-Furga G, Koleske AJ, Pendergast AM, Rottapel R: Reciprocal stabilization of ABL and TAZ regulates osteoblastogenesis through transcription factor RUNX2. J Clin Invest. 2016 Dec 1; 2016 Oct 31. PMID: 27797343

Wetzel DM, Rhodes EL, Li S, McMahon-Pratt D, Koleske AJ: The Src kinases Hck, Fgr and Lyn activate Arg to facilitate IgG-mediated phagocytosis and Leishmania infection. J Cell Sci. 2016 Aug 15; 2016 Jun 29. PMID: 27358479

Xiao X, Levy AD, Rosenberg BJ, Higley MJ, Koleske AJ: Disruption of Coordinated Presynaptic and Postsynaptic Maturation Underlies the Defects in Hippocampal Synapse Stability and Plasticity in Abl2/Arg-Deficient Mice. J Neurosci. 2016 Jun 22. PMID: 27335408


2015 (5) 

Katrancha SM, Koleske AJ: SNARE Complex Dysfunction: A Unifying Hypothesis for Schizophrenia.Biol Psychiatry. 2015 Sep 15. PMID: 26296424

Nygaard HB, Wagner AF, Bowen GS, Good SP, MacAvoy MG, Strittmatter KA, Kaufman AC, Rosenberg BJ, Sekine-Konno T, Varma P, Chen K, Koleske AJ, Reiman EM, Strittmatter SM, van Dyck CH: A phase Ib multiple ascending dose study of the safety, tolerability, and central nervous system availability of AZD0530 (saracatinib) in Alzheimer’s disease. Alzheimers Res Ther. 2015; 2015 Apr 14. PMID: 25874001

Ha BH, Simpson MA, Koleske AJ, Boggon TJ: Structure of the ABL2/ARG kinase in complex with dasatinib. Acta Crystallogr F Struct Biol Commun. 2015 Apr; 2015 Mar 20. PMID: 25849507

Simpson MA, Bradley WD, Harburger D, Parsons M, Calderwood DA, Koleske AJ: Direct interactions with the integrin β1 cytoplasmic tail activate the Abl2/Arg kinase. J Biol Chem. 2015 Mar 27; 2015 Feb 18. PMID: 25694433

Courtemanche N, Gifford SM, Simpson MA, Pollard TD, Koleske AJ: Abl2/Abl-related gene stabilizes actin filaments, stimulates actin branching by actin-related protein 2/3 complex, and promotes actin filament severing by cofilin. J Biol Chem. 2015 Feb 13; 2014 Dec 24. PMID: 25540195


2014 (6)

DePoy LM, Perszyk RE, Zimmermann KS, Koleske AJ, Gourley SL: Adolescent cocaine exposure simplifies orbitofrontal cortical dendritic arbors. Front Pharmacol. 2014; 2014 Oct 27. PMID: 25452728

Levy AD, Omar MH, Koleske AJ: Extracellular matrix control of dendritic spine and synapse structure and plasticity in adulthood. Front Neuroanat. 2014; 2014 Oct 20. PMID: 25368556

Cooper MA, Koleske AJ: Ablation of ErbB4 from excitatory neurons leads to reduced dendritic spine density in mouse prefrontal cortex. J Comp Neurol. 2014 Oct 1; 2014 Apr 29. PMID: 24752666

Gifford SM, Liu W, Mader CC, Halo TL, Machida K, Boggon TJ, Koleske AJ: Two amino acid residues confer different binding affinities of Abelson family kinase SRC homology 2 domains for phosphorylated cortactin. J Biol Chem. 2014 Jul 11; 2014 Jun 2. PMID: 24891505

Engel U, Zhan Y, Long JB, Boyle SN, Ballif BA, Dorey K, Gygi SP, Koleske AJ, Vanvactor D: Abelson phosphorylation of CLASP2 modulates its association with microtubules and actin. Cytoskeleton (Hoboken). 2014 Mar; 2014 Mar 12. PMID: 24520051

Kerrisk ME, Cingolani LA, Koleske AJ: ECM receptors in neuronal structure, synaptic plasticity, and behavior. Prog Brain Res. 2014. PMID: 25410355


2013 (10)

Kerrisk ME, Koleske AJ: Arg kinase signaling in dendrite and synapse stabilization pathways: memory, cocaine sensitivity, and stress. Int J Biochem Cell Biol. 2013 Nov; 2013 Aug 2. PMID: 23916785

Um JW, Kaufman AC, Kostylev M, Heiss JK, Stagi M, Takahashi H, Kerrisk ME, Vortmeyer A, Wisniewski T, Koleske AJ, Gunther EC, Nygaard HB, Strittmatter SM: Metabotropic glutamate receptor 5 is a coreceptor for Alzheimer aβ oligomer bound to cellular prion protein. Neuron. 2013 Sep 4. PMID: 24012003

Koleske AJ: Molecular mechanisms of dendrite stability. Nat Rev Neurosci. 2013 Aug; 2013 Jul 10. PMID: 23839597

Beaty BT, Sharma VP, Bravo-Cordero JJ, Simpson MA, Eddy RJ, Koleske AJ, Condeelis J: β1 integrin regulates Arg to promote invadopodial maturation and matrix degradation. Mol Biol Cell. 2013 Jun; 2013 Apr 3. PMID: 23552693

Gil-Henn H, Patsialou A, Wang Y, Warren MS, Condeelis JS, Koleske AJ: Arg/Abl2 promotes invasion and attenuates proliferation of breast cancer in vivo. Oncogene. 2013 May 23; 2012 Jul 9. PMID: 22777352

Bryce NS, Reynolds AB, Koleske AJ, Weaver AM: WAVE2 regulates epithelial morphology and cadherin isoform switching through regulation of Twist and Abl. PLoS One. 2013; 2013 May 15. PMID: 23691243

Kerrisk ME, Greer CA, Koleske AJ: Integrin α3 is required for late postnatal stability of dendrite arbors, dendritic spines and synapses, and mouse behavior. J Neurosci. 2013 Apr 17. PMID: 23595732

Couch BA, Kerrisk ME, Kaufman AC, Nygaard HB, Strittmatter SM, Koleske AJ: Delayed amyloid plaque deposition and behavioral deficits in outcrossed AβPP/PS1 mice. J Comp Neurol. 2013 Apr 15. PMID: 23047754

Gourley SL, Swanson AM, Koleske AJ: Corticosteroid-induced neural remodeling predicts behavioral vulnerability and resilience. J Neurosci. 2013 Feb 13. PMID: 23407965

Lin YC, Yeckel MF, Koleske AJ: Abl2/Arg controls dendritic spine and dendrite arbor stability via distinct cytoskeletal control pathways. J Neurosci. 2013 Jan 30. PMID: 23365224


2012 (9)

Gourley SL, Swanson AM, Jacobs AM, Howell JL, Mo M, Dileone RJ, Koleske AJ, Taylor JR: Action control is mediated by prefrontal BDNF and glucocorticoid receptor binding. Proc Natl Acad Sci U S A. 2012 Dec 11; 2012 Nov 26. PMID: 23185000

Furlan A, Lamballe F, Stagni V, Hussain A, Richelme S, Prodosmo A, Moumen A, Brun C, Del Barco Barrantes I, Arthur JS, Koleske AJ, Nebreda AR, Barilà D, Maina F: Met acts through Abl to regulate p53 transcriptional outcomes and cell survival in the developing liver. J Hepatol. 2012 Dec; 2012 Aug 10. PMID: 22889954

Deng Y, Couch BA, Koleske AJ, Turk BE: A peptide photoaffinity probe specific for the active conformation of the Abl tyrosine kinase. Chembiochem. 2012 Nov 26; 2012 Oct 18. PMID: 23081945

MacGrath SM, Koleske AJ: Arg/Abl2 modulates the affinity and stoichiometry of binding of cortactin to F-actin. Biochemistry. 2012 Aug 21; 2012 Aug 10. PMID: 22849492

Wetzel DM, McMahon-Pratt D, Koleske AJ: The Abl and Arg kinases mediate distinct modes of phagocytosis and are required for maximal Leishmania infection. Mol Cell Biol. 2012 Aug; 2012 Jun 4. PMID: 22665498

MacGrath SM, Koleske AJ: Cortactin in cell migration and cancer at a glance. J Cell Sci. 2012 Apr 1. PMID: 22566665

Warren MS, Bradley WD, Gourley SL, Lin YC, Simpson MA, Reichardt LF, Greer CA, Taylor JR, Koleske AJ: Integrin β1 signals through Arg to regulate postnatal dendritic arborization, synapse density, and behavior. J Neurosci. 2012 Feb 22. PMID: 22357865

Gourley SL, Olevska A, Warren MS, Taylor JR, Koleske AJ: Arg kinase regulates prefrontal dendritic spine refinement and cocaine-induced plasticity. J Neurosci. 2012 Feb 15. PMID: 22396406

Liu W, MacGrath SM, Koleske AJ, Boggon TJ: Lysozyme contamination facilitates crystallization of a heterotrimeric cortactin-Arg-lysozyme complex. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Feb 1; 2012 Jan 25. PMID: 22297987


2011 (6)

Magalhaes MA, Larson DR, Mader CC, Bravo-Cordero JJ, Gil-Henn H, Oser M, Chen X, Koleske AJ, Condeelis J: Cortactin phosphorylation regulates cell invasion through a pH-dependent pathway. J Cell Biol. 2011 Nov 28; 2011 Nov 21. PMID: 22105349

Cooper MA, Koleske AJ: ErbB4 localization to interneurons: clearer insights into schizophrenia pathology. Biol Psychiatry. 2011 Oct 1. PMID: 21924131

Chung C, Mader CC, Schmitz JC, Atladottir J, Fitchev P, Cornwell ML, Koleske AJ, Crawford SE, Gorelick F: The vacuolar-ATPase modulates matrix metalloproteinase isoforms in human pancreatic cancer.Lab Invest. 2011 May; 2011 Feb 21. PMID: 21339745

MacGrath SM, Koleske AJ: Invadopodia: RhoC runs rings around cofilin. Curr Biol. 2011 Apr 26. PMID: 21514509

Mader CC, Oser M, Magalhaes MA, Bravo-Cordero JJ, Condeelis J, Koleske AJ, Gil-Henn H: An EGFR-Src-Arg-cortactin pathway mediates functional maturation of invadopodia and breast cancer cell invasion. Cancer Res. 2011 Mar 1; 2011 Jan 21. PMID: 21257711

Gourley SL, Taylor JR, Koleske AJ: Cell adhesion signaling pathways: First responders to cocaine exposure? Commun Integr Biol. 2011 Jan. PMID: 21509173


2010 (3)

Oser M, Mader CC, Gil-Henn H, Magalhaes M, Bravo-Cordero JJ, Koleske AJ, Condeelis J: Specific tyrosine phosphorylation sites on cortactin regulate Nck1-dependent actin polymerization in invadopodia. J Cell Sci. 2010 Nov 1. PMID: 20971703

Peacock JG, Couch BA, Koleske AJ: The Abl and Arg non-receptor tyrosine kinases regulate different zones of stress fiber, focal adhesion, and contractile network localization in spreading fibroblasts.Cytoskeleton (Hoboken). 2010 Oct. PMID: 20737438

Ko HS, Lee Y, Shin JH, Karuppagounder SS, Gadad BS, Koleske AJ, Pletnikova O, Troncoso JC, Dawson VL, Dawson TM: Phosphorylation by the c-Abl protein tyrosine kinase inhibits parkin’s ubiquitination and protective function. Proc Natl Acad Sci U S A. 2010 Sep 21; 2010 Sep 7. PMID: 20823226